I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding.
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چکیده
منابع مشابه
Hypothermia enhances phosphorylation of I kappa B kinase and prolongs nuclear localization of NF-kappa B in LPS-activated macrophages
Hypothermia (HT) has been associated with both beneficial and detrimental consequences in various pathophysiologic states. While HT is generally thought to have anti-inflammatory and cytoprotective effects, we have previously shown that moderate in vitro HT prolongs TNFα production by LPS-stimulated mononuclear phagocytes, in part by prolonging TNFα gene transcription and activation of the plei...
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ژورنال
عنوان ژورنال: Molecular Biology of the Cell
سال: 1992
ISSN: 1059-1524,1939-4586
DOI: 10.1091/mbc.3.12.1339